Transatlantic Australasian Retroperitoneal Sarcoma Working Group

A collaborative group for Surgical Oncologists and Sarcoma Professionals

Open studies / projects

INTERNATIONAL MULTI-INSTITUTIONAL RESEARCH BY TARPSWG

Check out the Studies that have been done and are currently recruiting for Collaborative Research:

FOR MORE INFORMATION ON ANY OF THESE STUDIES PLEASE CONTACT: tarpswg@gmail.com

Studies open to accrual

TARPSWG-2008

Current Patterns of Care for Dermatofibrosarcoma Protuberans (DFSP) or DFSP with fibrosarcomatous transformation: A study by the TARPSWG

  • PIs: Jeffrey Farma MD (Fox Chase Cancer Center, Philadelphia, US)
  • Co-I: Leah Stockton, MD; Stephanie Greco, MD; Margaret von Mehren, MD (Fox Chase Cancer Center, Philadelphia, US)
  • Status: Approved and Open to Accrual
  • Eligibility: Any center can contribute to this study. Any DFSP diagnosed between Jan 2007 to Dec 2019 Minimum of 1 case required to enter the study

TARPSWG-2009

The Natural History of Well-differentiated Liposarcoma in the Retroperitoneum: A TARPSWG Study

  • PIs: Mark Fairweather, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US); Chandrajit Raut, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US)
  • Status: Approved and Open to Accrual
  • Eligibility: Any center can contribute to this study. All patients who have undergone resection of a primary well-differentiated liposarcoma who underwent surgery for a local or distant recurrence between January 1st, 2002 and December 31st, 2017. Absence of dedifferentiated component must be confirmed on original pathology report. Minimum of 1 case required to enter the study

TARPSWG-R1901 (RESAR Project)

Evaluating a Surgical Complexity Score to predict complications Post-Resection of a Retroperitoneal Sarcoma: A study by the Trans-Atlantic Australasian RPS Working Group (TARPSWG).

  • PI: Mark Fairweather, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US)
  • Co-I: Chandrajit Raut, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US)
  • Status: Approved and Open to Accrual to RESAR Centers that enrolled patients between Jan 2017 and Jan 2020
  • Eligibility: Must be a RESAR center to participate, Must have updated census to Jan 31, 20202; additional information on date of post-operative complication will be required

TARPSWG-R1905 (RESAR Project)

Accuracy and Concordance of Biopsy Diagnosis in Retroperitoneal Sarcoma (BISARC): An International Multi-Institutional Prospective Study by the Trans-Atlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG)

  • PIs: Sinziana Dumitra, MD (MgGill University Health Center, Montreal, Canada) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)
  • Co-I: Max Almond, MD (University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK)
  • Status: Approved and Open to Accrual for RESAR Centers
  • Eligibility: Must be a RESAR center to participate, Must have updated census to Dec 31, 2019 and have additional data point of histology on Biopsy

Published papers

TARPSWG-2007

Virtual Biobanking for Retroperitoneal Sarcoma: A Transatlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG) Initiative

PIs: Rebecca Gladdy Md, PhD (University of Toronto); Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)

Publication: https://link.springer.com/article/10.1245%2Fs10434-020-08775-1

TARPSWG-1903

Patterns of Recurrence and Survival Probability following Second Relapse of Retroperitoneal Sarcoma: A Study from TARPSWG

  • PIs: Winan vanHoudt, MD (The Netherlands Cancer Institute, Amsterdam Netherlands) ; Rebecca Gladdy, MD, PhD (Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada)
  • Co-I: Marco Fiore, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan Italy)

TARPSWG-1700

Intercontinental Collaborative Experience with abdominal, retroperitoneal and pelvic schwannomas.

  • PIs: Sam Ford MD, PhD (University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)

TARPSWG-1701

Predicting Survival in Patients Undergoing Resection for Locally Recurrent Retroperitoneal Sarcoma: A Study and Novel Nomogram from TARPSWG

  • PIs: Chandrajit Raut, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)

TARPSWG-1702

Pancreaticoduodenectomy in the surgical management of primary retroperitoneal sarcoma.

  • PIs: William Tseng MD (University of Southern California, Keck School of Medicine, LA, US ) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)

TARPSWG-1806

Identifying the Minimum Volume Threshold for Retroperitoneal Soft Tissue Sarcoma Resection: Merging National Data with Consensus Expert Opinion.

  • PIs: Waddah Al-Rafaie, MD (MedStar Georgetown University Hospital, Washington, DC)
  • Co-Is: Anthony M. Villano, MD, Alexander Zeymo, MS, Suzanne O’Neill, PhD, (MedStar Georgetown University Hospital, Washington, DC)

TARPSWG

Variability in Patterns of Recurrence After Resection of Primary Retroperitoneal Sarcoma (RPS) A Report on 1007 Patients From the Multi-institutional Collaborative RPS Working Group

  • PIs: Chandrajit Raut, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)
  • Co-Is: Carol Swallow (University of Toronto); Dirk Strauss (Royal Marsden); Sylvie Bonavalot (Institut Curie) et al.

TARPSWG

Post-relapse Outcomes After Primary Extended Resection of Retroperitoneal Sarcoma: A Report From the Trans-Atlantic RPS Working Group

  • PIs: Carol Swallow (University of Toronto); Andrea MacNeill (Vancouver)
  • Co-Is: Chandrajit Raut, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy); Dirk Strauss (Royal Marsden); Sylvie Bonavalot (Institut Curie) et al.

TARPSWG

Postoperative Morbidity After Radical Resection of Primary Retroperitoneal Sarcoma A Report From the Transatlantic RPS Working Group

  • PIs: Dirk Strauss (Royal Marsden); Andrea MacNeill (Vancouver)
  • Co-Is: Chandrajit Raut, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy); Sylvie Bonavalot (Institut Curie); Carol Swallow (Unvisersity of Toronto) et al.
  • Publication:https://tarpswg.files.wordpress.com/2017/05/morbidity-tarpswg.pdf

TARPSWG

Radiotherapy for retroperitoneal liposarcoma: A report from the Transatlantic Retroperitoneal Sarcoma Working Group

  • PIs: Rick Hass (The Netherlands Cancer Institute); Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)
  • Co-Is: Chandrajit Raut, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US) ; Sylvie Bonavalot (Institut Curie); Carol Swallow (Unvisersity of Toronto); Piotr Rutkowski (Maria Sklodowska‐Curie Institute–Oncology Center) et al.

TARPSWG

External validation of a multi-institutional retroperitoneal sarcoma nomogram

  • PIs: Chandrajit Raut, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US); Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)
  • Co-Is: Sylvie Bonavalot (Institut Curie); Carol Swallow (Unvisersity of Toronto); Piotr Rutkowski (Maria Sklodowska‐Curie Institute–Oncology Center); Peter Hohenberger (Mannheim University); Dirk Strauss (Royal Marsden) et al.

TARPSWG – CONSENSUS

Management of Primary Retroperitoneal Sarcoma (RPS) in the Adult: A Consensus Approach From the Trans-Atlantic RPS Working Group

TARPSWG – CONSENSUS

Management of Recurrent Retroperitoneal Sarcoma (RPS) in the Adult: A Consensus Approach from the Trans-Atlantic RPS Working Group

TARPSWG – CONSENSUS

Management of metastatic retroperitoneal sarcoma: a consensus approach from the Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG)

Closed studies – manuscripts in progress

TARPSWG-2001

The Evaluation and Outcome of Mesenteric and Intra-Abdominal Desmoids: A study by the Trans-Atlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG)

  • PIs: Carolyn Nessim, MD, MSc (The Ottawa Hospital, Ottawa, Canada) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)
  • Co-I: Kerianne Boulva, MD (The Ottawa Hospital, Ottawa, Canada)
  • Status: Closed, Receiving Data from Centers

TARPSWG-2003

The Natural History of Ganglioneuroma: A Study by the Trans-Atlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG)

  • PI: Jason Sicklick, MD (Moores Cancer Center, University of California San Diego Health System, San Diego, US)
  • Co-Is: Sangkyu Noh, MS (Moores Cancer Center, University of California San Diego Health System, San Diego, US) ; Carolyn Nessim, MD, MSc, (The Ottawa Hospital, Ottawa, Canada)
  • Status: Closed, Receiving Data from Centers

TARPSWG-1801

Defining the Role of Neo-Adjuvant Systemic Therapy in High Risk Retroperitoneal Sarcoma: A Multi-Institutional TARPSWG Study

  • PIs: William Tseng MD (University of Southern California, Keck School of Medicine, LA, US ) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)
  • Status: Closed, Manuscript Submitted to Cancer

TARPSWG-1802

Postoperative pancreatic fistula following distal pancreatectomy for primary retroperitoneal sarcoma: an analysis by the Trans-Atlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG)

  • PIs: Sanjay Bagaria, MD (Mayo Clinic, Jacksonville, US) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)
  • Status: Closed, Manuscript Submitted to Annals of Surgical Oncology

TARPSWG-1803

Retroperitoneal Myxoid LPS: Always a Metastasis? A study by the Trans-Atlantic Australasian RPS Working Group (TARPSWG).

  • PIs: Carolyn Nessim, MD, MSc (The Ottawa Hospital, Ottawa, Canada) ; Chandrajit, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US)
  • Co-I: Bibianna Purgina, MD (The Ottawa Hospital, Ottawa, Canada)
  • Status: Closed, Currently Analyzing Data

TARPSWG-1804

Primary Mesenteric Sarcomas – A Collaborative experience by the Trans-Atlantic Australasian RPS Working Group (TARPSWG).

  • PIs: Sam Ford, MD, PhD ; Hannah Tattersall, MD (University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK)
  • Co-I: Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)
  • Status: Closed, Manuscript Submitted to European Journal of Surgical Oncology

TARPSWG-1805

STREXIT – “off trial” management and outcomes of primary non-metastatic RPS at centres that participated in the STRASS trial

  • PIs: Carol Swallow, MD, PhD (Mount Sinai Hospital, Princess Margaret Hospital, University of Toronto, Toronto, Canada) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy) ; Chandrajit Raut, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US) ;Sylvie Bonvalot, MD (Institut Curie, PSL University, Paris, France)
  • Status: Closed, Manuscript in Progress

TARPSWG-1807

Pelvic Sarcomas – Retrospective Analysis of Clinical and Surgical Features and Outcomes (PELVISARC): A study by the Trans-Atlantic Australasian RPS Working Group (TARPSWG).

  • PIs: Marco Fiore, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy) ; Sinziana Dumitra, MD (MgGill University Health Center, Montreal, Canada)
  • Co-I: Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)
  • Status: Closed, Currently Analyzing Data

TARPSWG-1902

Postoperative Morbidity After Resection of Recurrent Retroperitoneal Sarcoma: A Report from the Trans-Atlantic Australasian RPS Working Group (TARPSWG).

  • PIs: Carolyn Nessim, MD, MSc (The Ottawa Hospital, Ottawa, Canada); Guy Lahat, MD, (Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel)
  • Co-Is: Chandrajit Raut, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)
  • Status: Closed, Manuscript Submitted to Annals of Surgical Oncology

An Analysis on Differentiation Changes and Outcomes at the Time of First Recurrence of Retroperitoneal Liposarcoma by the Trans-Atlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG)

  • PIs: Carolyn Nessim, MD, MSc (The Ottawa Hospital, Ottawa, Canada); Sanjay P Bagaria, MD, (Mayo Clinic, Jacksonville, US)
  • Co-Is: Chandrajit Raut, MD (Brigham and Women’s Hospital and Dana-Farber Cancer Institute, Boston, US) ; Alessandro Gronchi, MD (Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy)
  • Status: Closed, Manuscript in Progress

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