This is a retrospective analysis of 681 patients from 22 Trans-Atlantic Australasian Retroperitoneal Sarcoma Working Group (TARPSWG) centers. The results showed that surgical approach to recurrent RPS is relatively safe and comparable with primary RPS in terms of complications and postoperative mortality when performed at specialized sarcoma centers. Thus, resection of a recurrent RPS is a reasonable option. In the multivariable analysis, a transfusion requirement was found to be a significant predictor of major complications and worse overall survival; therefore every effort should be made to minimize the need for blood transfusions.
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